Many studies have demonstrated the influence of environmental determinants on the occurrence of stroke. However, the exact nature of the effects related to these factors (synergistic, confounding, mediation...) remains unknown to date.
The main objective of this study is to analyze, in urban areas, the relationship between stroke occurrence and multiple exposure to air pollution, noise, and the potential benefits of proximity to green and blue spaces in the living environment. Nitrogen dioxide (NO2) and particulates (PM10) will be considered to assess exposure to air pollution. Proximity and accessibility to green and blue spaces will also be included in the assessment. The secondary objective is to evaluate the relative contribution of each of these factors and their possible interaction.
A case-control study will be set up with Dijon residents, in collaboration with the Dijon University Hospital and the Dijon stroke registry. The level of exposure to the various environmental factors of the cases (person having presented a first stroke between January 1, 2016 and March 1, 2020 at the Dijon University Hospital) will be compared to the level of exposure of the controls. The controls will be adult patients hospitalized at the Dijon University Hospital for a reason unrelated to a cardiovascular event and without a history of such an event, treated over the same period 2016-2020 and residing in the city of Dijon.
