
Site Hauts du Chazal
UMR 6249 Chrono-environnement
19 rue Ambroise Paré
25030 Besançon cedex
France
Adeline Rouzet-San
Senior Engineer – CHU Besançon
PATHOGENES
adeline.rouzet@-Code to remove to avoid SPAM-univ-fcomte.fr
+33 (0)3 63 08 22 34, room R28 (HdC)
Hypersensitivity pneumonitis – Proteomic – Recombinant antigens – Molecular biology – Serological tests – ELISA – Environmental analyses
Presentation
Development of standardised, high-performance serological tests for the serological diagnosis of various forms of hypersensitivity pneumonitis (lung disease).
Analysis of patient environment, production of antigens directly from micro-organisms / droppings collected from patients, visualisation of protein profiles (SDS PAGE electrophoresis), then analysis of patients sensitisation to these antigens using serological tests (ELISA, Western blot 1D/ 2D). Production of recombinant proteins in the E.Coli system.
Projects
- HOME-HP (data manager)
- Goat farmers serology (Netherland)
Publications
Journal articles
2025
- ref_biblio
- François Gillet, Adeline Rouzet, Daniel Borcard, Pierre Legendre. Rarity and sparseness in plant communities: impact of minor species removal on beta diversity and canonical ordination. Journal of Vegetation Science, 2025, 36 (1), pp.e70013. ⟨10.1111/jvs.70013⟩. ⟨hal-04924382⟩
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2022
- ref_biblio
- A Bellanger, S Lallemand, A Tumasyan Horikian, J Navellou, C Barrera, et al.. Investigation of the value of precipitins in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients with a positive marker for Aspergillus species. Medical Mycology, 2022, 60 (5), ⟨10.1093/mmy/myac031⟩. ⟨hal-05008599⟩
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- ref_biblio
- Adeline Rouzet, Ferran Morell, Gabriel Reboux, Ana Villar, Laurence Millon, et al.. Pilot Study Using Recombinant Antigens r-PROE and r-IGLL1 for the Serodiagnosis of Feather Duvet Lung. Archivos de Bronconeumología, 2022, 58 (7), pp.554-560. ⟨10.1016/j.arbres.2021.02.011⟩. ⟨hal-04095932⟩
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- ref_biblio
- Adeline Rouzet, Emeline Scherer, Coralie Barrera, Anne Gondouin, Gabriel Reboux, et al.. Bird fancier's lung serodiagnosis by automated r-IgLL1 ELISA. Journal of Immunological Methods, 2022, 505, pp.113267. ⟨10.1016/j.jim.2022.113267⟩. ⟨hal-03713088⟩
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2021
- ref_biblio
- Adeline Rouzet, Ferran Morell, Gabriel Reboux, Ana Villar, Laurence Millon, et al.. Pilot Study Using Recombinant Antigens r-PROE and r-IGLL1 for the Serodiagnosis of Feather Duvet Lung. Archivos de Bronconeumología, 2021, ⟨10.1016/j.arbres.2021.02.011⟩. ⟨hal-03316098⟩
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2020
- ref_biblio
- Steffi Rocchi, Gabriel Reboux, Emeline Scherer, Audrey Laboissière, Cécile Zaros, et al.. Indoor Microbiome: Quantification of Exposure and Association with Geographical Location, Meteorological Factors, and Land Use in France. Microorganisms, 2020, 8 (3), pp.341. ⟨10.3390/microorganisms8030341⟩. ⟨hal-02543250⟩
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2019
- ref_biblio
- Anne-Pauline Bellanger, Gabriel Reboux, Adeline Rouzet, Coralie Barrera, Steffi Rocchi, et al.. Hypersensitivity pneumonitis: A new strategy for serodiagnosis and environmental surveys. Respiratory Medicine, 2019, 150, pp.101-106. ⟨10.1016/j.rmed.2019.02.019⟩. ⟨hal-02307827⟩
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2017
- ref_biblio
- Adeline Rouzet, Gabriel Reboux, Jean-Charles Dalphin, Anne Gondouin, Paul de Vuyst, et al.. An immunoproteomic approach revealed antigenic proteins enhancing serodiagnosis performance of bird fancier's lung. Journal of Immunological Methods, 2017, 450, pp.58 - 65. ⟨10.1016/j.jim.2017.07.012⟩. ⟨hal-01664277⟩
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- ref_biblio
- Adeline Rouzet, Gabriel Reboux, Jean-Charles Dalphin, Paul de Vuyst, Audrey Laboissière, et al.. Usefulness of à la carte antigens for bird fancier’s lung serodiagnosis: total dropping extract and/or dropping’s microflora antigens. Journal of Medical Microbiology, 2017, 66 (10), pp.1467 - 1470. ⟨10.1099/jmm.0.000586⟩. ⟨hal-01667609⟩
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2016
- ref_biblio
- A. Rouzet, G. Reboux, C. Barrera, B. Rognon, J.C. Dalphin, et al.. Identification et spécificité d’espèce des protéines d’intérêt pour le diagnostic sérologique de la maladie du poumon d’éleveur d’oiseaux. Revue des Maladies Respiratoires, 2016, 33, ⟨10.1016/j.rmr.2015.10.656⟩. ⟨hal-01305533⟩
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2014
- ref_biblio
- Adeline Rouzet, Gabriel Reboux, Benedicte Rognon, Coralie Barrera, Paul de Vuyst, et al.. Immunogenic proteins specific to different bird species in Bird Fancier's Lung disease. Journal of Toxicology and Environmental Health, Part A: Current Issues, 2014, pp.1-5. ⟨hal-00942632⟩
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- ref_biblio
- Adeline Rouzet, Gabriel Reboux, Bénédicte Rognon, Coralie Barrera, Paul de Vuyst, et al.. Immunogenic Proteins Specific to Different Bird Species in Bird Fancier’s Lung. Journal of Toxicology and Environmental Health, Part A: Current Issues, 2014, 77 (12), pp.724 - 730. ⟨10.1080/15287394.2014.889616⟩. ⟨hal-01667642⟩
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Conference papers
2014
- ref_biblio
- Gabriel Reboux, Adeline Rouzet, Benedicte Rognon, Coralie Barrera, Paul de Vuyst, et al.. Species Specificity of Immunogenic Proteins in Bird Fancier's Lung Disease.. B50-OCCUPATIONAL AND ENVIRONMENTAL EXPOSURES AND EFFECTS: INTERDISCIPLINARY SESSION, May 2014, San Diego, United States. ⟨hal-00942702⟩
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2013
- ref_biblio
- François Gillet, Leslie Mauchamp, Adeline Rouzet. Regional rarity versus local scarcity in plant communities: Impact of species removal on model performance in constrained ordination. 56th IAVS Symposium, 2013, Tartu, Estonia. pp.73. ⟨hal-00927303⟩
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Theses
2017
- ref_biblio
- Adeline Rouzet. Identification des protéines antigéniques impliquées dans la maladie du poumon d’éleveur d’oiseaux. Biochimie, Biologie Moléculaire. Université Bourgogne Franche-Comté, 2017. Français. ⟨NNT : 2017UBFCE014⟩. ⟨tel-01831605⟩
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